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PXD075407

PXD075407 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomics of Mouse Testicular Organoids on Day 6
DescriptionTo investigate the mechanism for the formation of tubule-like structures in testicular organoids, we conducted proteomic analysis on O-Torgs and T-Torgs at day 6. Through differential protein expression and enrichment analysis, it was found that the extracellular matrix (ECM) related pathways in O-Orgs were significantly upregulated. This indicates that the ECM might facilitate the formation of tubule-like structures in O-Orgs, which might be important for spermatogenesis.
HostingRepositoryPRIDE
AnnounceDate2026-03-26
AnnouncementXMLSubmission_2026-03-26_09:27:01.225.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterQi Li
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumenttimsTOF HT
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-03-09 09:45:37ID requested
12026-03-26 09:27:01announced
Publication List
10.1038/S41467-026-71254-W;
Keyword List
submitter keyword: LC-MSMS,Mouse, Testicular organoids
Contact List
Xiao-Yang Zhao
contact affiliationState Key Laboratory of Organ Failure Research, School of Laboratory Medicine and Biotechnology, Southern Medical University
contact emailzhaoxiaoyang@smu.edu.cn
lab head
Qi Li
contact affiliationSouthern Medical University
contact emaillq952166@163.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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