PXD075345

PXD075345 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	BLM-G4 pulldown IP-MS in human colon cancer HT-29 cells
Description	the experiment uses biotin-labelled BLM-G4 to incubate with HT-29 cell lysates, and uses streptavidin agarose beads to pulldown BLM-G4-binding proteins. Utilize LC-MS/MS to annotate and quantify the proteins pulled down by BLM-G4.
HostingRepository	PRIDE
AnnounceDate	2026-06-08
AnnouncementXML	Submission_2026-06-08_01:28:47.070.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yingying Wang
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-03-07 01:33:04	ID requested
⏵ 1	2026-06-08 01:28:48	announced

Publication List

Wang Y, Zhang X, Bian Y, He S, Cheng R, Li J, Dickerhoff J, Liu Y, Zhou Y, Bian J, Zheng K, Yang D, Kong LY, Wang KB, A small molecule disrupts G4-STAT1 interaction and synergizes with olaparib to drive cancer cell death. Nucleic Acids Res, 54(9):(2026) [pubmed]
10.1093/nar/gkag383;

Wang Y, Zhang X, Bian Y, He S, Cheng R, Li J, Dickerhoff J, Liu Y, Zhou Y, Bian J, Zheng K, Yang D, Kong LY, Wang KB, A small molecule disrupts G4-STAT1 interaction and synergizes with olaparib to drive cancer cell death. Nucleic Acids Res, 54(9):(2026) [pubmed]

10.1093/nar/gkag383;

Keyword List

ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: pulldown,BLM-G4, IP-MS, HT-29 cell

ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project

submitter keyword: pulldown,BLM-G4, IP-MS, HT-29 cell

Contact List

Kaibo Wang
contact affiliation	China Pharmaceutical University
contact email	kbwang@cpu.edu.cn
lab head
Yingying Wang
contact affiliation	China Pharmaceutical University
contact email	1377599356@qq.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD075345
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD075345

PRIDE project URI

Repository Record List

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