PXD075243

PXD075243 is an original dataset announced via ProteomeXchange.

Title	Mass Spectrometry Identification of LncRNA606938 Interacting Proteins
Description	This study aims to systematically identify protein molecules that specifically interact with the long non-coding RNA LncRNA606938 using mass spectrometry technology, thereby revealing its potential biological functions and molecular regulatory mechanisms. An RNA pull-down assay strategy was employed, involving in vitro transcription and labeling of LncRNA606938 as bait to enrich specifically bound protein complexes from cell lysates. The eluted complexes were subsequently analyzed using high-resolution liquid chromatography-tandem mass spectrometry. Through database alignment and bioinformatics analysis, candidate proteins interacting with LncRNA606938 were identified. A protein-protein interaction network associated with LncRNA606938 was constructed, providing key clues for further exploration of its involvement in specific biological processes such as transcriptional regulation, RNA processing, and signal transduction.
HostingRepository	iProX
AnnounceDate	2026-03-04
AnnouncementXML	Submission_2026-03-04_19:25:53.933.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jin'e Du
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2026-03-04 19:25:39	ID requested
⏵ 1	2026-03-04 19:25:54	announced

Dataset with its publication pending

submitter keyword: LncRNA606938, RNA pull-down, LC-MS/MS

Haili Wu
contact affiliation	Shanxi University
contact email	whl@sxu.edu.cn
lab head
Jin'e Du
contact affiliation	Shanxi University
contact email	dujine09@163.com
dataset submitter

iProX dataset URI