⮝ Full datasets listing
PXD075239
PXD075239 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | TEO-GalNAc: Tag-free Chemoenzymatic Enrichment and Quantitative Mapping of Tn/T Antigen Sialylation Occupancy via Ketone-Oxime Chemistry |
| Description | TEO-GalNAc is a chemoenzymatic strategy for tag-free enrichment and quantitative mapping of Tn/T O-GalNAc glycopeptides. Ketone-modified CMP-Sia is transferred by ST6GalNAc1 for selective tagging, followed by reversible oxime capture using hydroxylamine beads. Mild acid release enables tag-free recovery and quantitative assessment of sialylation occupancy on core GalNAc residues in complex samples. |
| HostingRepository | iProX |
| AnnounceDate | 2026-03-04 |
| AnnouncementXML | Submission_2026-03-04_18:55:12.831.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Li Liu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-03-04 18:54:27 | ID requested | |
| ⏵ 1 | 2026-03-04 18:55:13 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Tn/T antigens, tag-free chemoenzymatic enrichment, sialylation-occupancy, one-step labeling, ketone-mediated tagging |
Contact List
| Mingliang Ye | |
|---|---|
| contact affiliation | Dalian Institute of Chemical Physics, Chinese Academy of Sciences |
| contact email | mingliang@dicp.ac.cn |
| lab head | |
| Li Liu | |
| contact affiliation | Dalian Institute of Chemical Physics, Chinese Academy of Sciences |
| contact email | leigh1809@dicp.ac.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
