PXD075230

PXD075230 is an original dataset announced via ProteomeXchange.

Title	Bulk proteomics of porcine skin excision injury at 15 minutes and 4 hours post wounding.
Description	We aimed to define the early molecular events of porcine skin excision injury by investigating at 15 minutes and 4 hours post-wounding. Our objective was to compare time points to identify proteins and pathways that initiate, sustain, or modulate the injury response, including signaling, cytoskeletal dynamics, inflammation, and early repair processes. Using TMT-based quantitative LC–MS/MS on porcine skin tissue, we sought to generate a high-confidence, time-resolved proteomic map that highlights key regulators and potential therapeutic targets in the immediate and short-term phases after injury. We preformed phospho-proteomics analysis to capture rapid, site-specific phosphorylation changes that report on signaling pathway activation.
HostingRepository	PRIDE
AnnounceDate	2026-03-31
AnnouncementXML	Submission_2026-03-30_23:15:38.721.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Markus Hartl
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: NEWT:9825;
ModificationList	phosphorylated residue
Instrument	Orbitrap Exploris 480

Revision	Datetime	Status	ChangeLog Entry
0	2026-03-04 13:10:10	ID requested
⏵ 1	2026-03-30 23:15:39	announced

Dataset with its publication pending

submitter keyword: None

Mikolaj Ogrodnik
contact affiliation	Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, Austrian Cluster for Tissue Regeneration, The laboratory for Tissue Damage Responses in Regeneration and Aging, Donaueschingenstrasse 13, A-1200 Vienna, Austria,
contact email	mikolaj.ogrodnik@lbg.ac.at
lab head
Markus Hartl
contact affiliation	Max Perutz Labs, Mass Spectrometry Facility, Vienna Biocenter Campus (VBC), Dr. Bohr-Gasse 9, Vienna, Austria
contact email	proteomics@maxperutzlabs.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD075230

PRIDE project URI

• PRIDE
  1. PXD075230
     1. Label: PRIDE project
     2. Name: Bulk proteomics of porcine skin excision injury at 15 minutes and 4 hours post wounding.