⮝ Full datasets listing
PXD075014
PXD075014 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative Lactylation Modification Proteomics of AC16 |
| Description | In this study, utilizing both in vivo (LAD-operated mice) and in vitro (hypoxic AC16 cardiomyocytes) models, we have identified PFKP-K688 site lactylation (PFKP-K688la) as a crucial metabolic regulatory target in myocardial hypoxia. Through lactated proteomics analysis, we detected 521 Kla modified proteins, with PFKP emerging as the principal target of Kla modification. |
| HostingRepository | iProX |
| AnnounceDate | 2026-02-27 |
| AnnouncementXML | Submission_2026-02-27_19:04:13.911.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Cui Liu |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | lactic acid; TMT6plex reporter fragment |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-02-27 19:03:39 | ID requested | |
| ⏵ 1 | 2026-02-27 19:04:14 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Myocardial ischemia, lactic acid, lactylation, glycolysis, PFKP |
Contact List
| Peiqing Liu | |
|---|---|
| contact affiliation | Sun Yat-sen University |
| contact email | liupq@mail.sysu.edu.cn |
| lab head | |
| Cui Liu | |
| contact affiliation | Sun Yat-sen University |
| contact email | 602148806@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
