⮝ Full datasets listing
PXD074927
PXD074927 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | IP-MS and proteomic analysis of GPR75-interacting proteins in the liver of CDAHFD-induced mice |
| Description | To investigate the mechanism by which GPR75 promotes metabolic dysfunction-associated steatohepatitis (MASH), we performed proteomic analysis on liver tissues from CDAHFD-fed control and hepatocyte-specific Gpr75-knockdown mice. To identify GPR75-interacting proteins, immunoprecipitation coupled with mass spectrometry (IP-MS) was conducted.The SCIEX Triple TOF 5600+ mass spectrometer was used in an information-dependent mode (IDA) to automatically switch between MS and MS/MS spectra. Data were analyzed using ProteinPilot™ software (SCIEX, Concord, ON, Canada) and the UniProtKB database. |
| HostingRepository | iProX |
| AnnounceDate | 2026-02-26 |
| AnnouncementXML | Submission_2026-02-25_19:08:50.541.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xule Yang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-02-25 19:07:43 | ID requested | |
| ⏵ 1 | 2026-02-25 19:08:51 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: GPR75, CDAHFD, Proteomic analysis, IP-MS |
Contact List
| Yuan Xie | |
|---|---|
| contact affiliation | China Pharmaceutical University |
| contact email | yuanxie@cpu.edu.cn |
| lab head | |
| Xule Yang | |
| contact affiliation | China Pharmaceutical University |
| contact email | yangxule0505@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
