PXD074925

PXD074925 is an original dataset announced via ProteomeXchange.

Title	IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration.
Description	. In the present study, we investigated if and how IRE1 could regulate the functionality of the secretory machinery in GB cells and identified GOLIM4, a Golgi-associated molecule whose expression is regulated downstream of IRE1 through the transcription of XBP1s.
HostingRepository	PRIDE
AnnounceDate	2026-03-02
AnnouncementXML	Submission_2026-03-02_07:07:57.147.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Luc Negroni
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-25 17:13:47	ID requested
⏵ 1	2026-03-02 07:07:57	announced

Dataset with its publication pending

submitter keyword: IRE1, GOLIM4,glioblastoma, secretome

Tony Avril
contact affiliation	INSERM UMR1242 and Centre Eugène Marquis, Rennes, France
contact email	t.avril@rennes.unicancer.fr
lab head
Luc Negroni
contact affiliation	CNRS
contact email	lnegroni@unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD074925

PRIDE project URI

• PRIDE
  1. PXD074925
     1. Label: PRIDE project
     2. Name: IRE1-dependent GOLIM4 expression controls protein secretion to modulate glioblastoma cell adhesion and migration.