PXD074858

PXD074858 is an original dataset announced via ProteomeXchange.

Title	Proteomic data of the perinatal pig brain
Description	The uploaded proteome data were obtained from 336 samples of perinatal Bama miniature pigs, covering multiple time points and brain regions. Analyzed with transcriptome data, they revealed the spatiotemporal organization of perinatal molecular profiles and gene-protein expression concordance. These data helped confirm perinatal Bama miniature pigs as an optimal large-animal model for human perinatal neurodevelopment (closer to humans than mice). They also identified a pan-regional developmental inflection point (E94-E104) with dramatic changes in proteins related to synaptogenesis and gliogenesis, supported analyses of regional developmental heterogeneity, and facilitated studying brain disorder risk gene transitions, serving as a key part of the multi-omics atlas for decoding neurodevelopmental pathogenesis.
HostingRepository	iProX
AnnounceDate	2026-02-24
AnnouncementXML	Submission_2026-02-24_23:29:24.421.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ziming Wang
SpeciesList	scientific name: Sus scrofa domesticus; NCBI TaxID: 9825;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF HT

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-24 23:29:06	ID requested
⏵ 1	2026-02-24 23:29:24	announced

Dataset with its publication pending

submitter keyword: Proteomic Data, Bama miniature pig, Brain

Mingfeng Li
contact affiliation	Huazhong University of Science and Technology
contact email	mingfengli@hust.edu.cn
lab head
Ziming Wang
contact affiliation	Huazhong University of Science and Technology
contact email	m202475814@hust.edu.cn
dataset submitter

iProX dataset URI