PXD074853

PXD074853 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomic analysis reveals that metal ion homeostasis and redox state influence the growth of Aeromonas hydrophila LP-2
Description	This project focuses on the proteomic analysis of metal ion homeostasis and redox state influence the growth of Aeromonas hydrophila LP-2 in Aeromonas hydrophila LP-2. In this study, we used DIA-based quantitative proteomics to profile LP-2 under TPEN (an efficient chelator of metal ion enzyme cofactors) exposure and found a total of 371 proteins were upregulated and 268 were downregulated. Bioinformatic analyses revealed that some of the differential abundance proteins (DAPs) were enriched in several Gene Ontology (GO) terms and KEGG pathways, such as Ion transport, Oxidoreductase activity, Periplasmic space and Microbial metabolism in diverse environments. The study utilizes advancedproteomics techniques, including LC-MS/MS, to uncoverdifferential protein expression patterns.
HostingRepository	iProX
AnnounceDate	2026-02-23
AnnouncementXML	Submission_2026-02-24_23:13:50.348.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chenghao Shen
SpeciesList	scientific name: Aeromonas hydrophila subsp. hydrophila ATCC 7966; NCBI TaxID: 380703;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Exploris 240

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-24 23:12:43	ID requested
⏵ 1	2026-02-24 23:13:50	announced

Dataset with its publication pending

submitter keyword: Ion homeostasis, redox state, TPEN,vQuantitative proteomics, A. hydrophila LP-2

Xiangmin Lin
contact affiliation	Fujian Agriculture and Forestry University
contact email	313461278@qq.com
lab head
Chenghao Shen
contact affiliation	Fujian Agriculture and Forestry University
contact email	316627587@qq.com
dataset submitter

iProX dataset URI