PXD074845 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Poultry handling-related stress alters membrane composition, extracellular vesicle production, survival, and virulence in Campylobacter jejuni Bf |
| Description | We investigated the adaptation of the aerotolerant Campylobacter jejuni Bf strain to conditions mimicking the poultry slaughter process. We showed that C. jejuni Bf survives and actively multiplies under combined thermal and oxidative stress. Stress exposure induces cell rounding, loss of motility, remodeling of membrane composition, decreased membrane fluidity, and metabolic reprogramming with increased intracellu lar ATP levels. While maintaining the lipid composition of its plasma membrane, C. jejuni modulates the lipid composition of its extracellular vesicles when exposed to stress. Notably, stressed C. jejuni cells release extracellular vesicles with increased toxicity toward the epithelial barrier of Caco-2 cells, potentially facilitating invasion of the gut epithelium. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-08-13 |
| AnnouncementXML | Submission_2026-08-13_04:06:22.212.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Zoran Minic |
| SpeciesList | scientific name: Campylobacter jejuni; NCBI TaxID: NEWT:197; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-02-24 22:54:17 | ID requested | |
| ⏵ 1 | 2026-08-13 04:06:22 | announced | |
Publication List
Keyword List
| submitter keyword: Campylobacter jejuni |
| bacterial adaptation |
| oxidative and thermic stress |
| extracellular vesicles |
Contact List
| Jasmina Vidic |
|---|
| contact affiliation | Université Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, Jouy en Josas, France |
| contact email | jasmina.vidic@inrae.fr |
| lab head | |
| Zoran Minic |
|---|
| contact affiliation | John L. Holmes Mass Spectrometry Facility, University of Ottawa |
| contact email | zminic@uottawa.ca |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD074845 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD074845
- Label: PRIDE project
- Name: Poultry handling-related stress alters membrane composition, extracellular vesicle production, survival, and virulence in Campylobacter jejuni Bf
