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PXD074844

PXD074844 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCell Atlas Analyses Reveals the Anti-proteolytic Fibroblast Subset as a protector in the Abdominal Aortic Aneurysm
DescriptionTo elucidate the composition of transcriptional complexes involving Nfkb1 in the context of abdominal aortic aneurysm (AAA), we performed co-immunoprecipitation followed by mass spectrometry (Co-IP MS) using an anti-Nfkb1 antibody in murine vascular adventitial fibroblasts overexpressing Nfkb1. Three biological replicates were analyzed (IP-1, IP-2, and IP-3). The goal was to identify protein components that physically interact with Nfkb1, potentially constituting transcriptional co-regulators within the nuclear environment.
HostingRepositoryiProX
AnnounceDate2026-02-21
AnnouncementXMLSubmission_2026-02-24_22:54:05.637.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuehong Zheng
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-02-24 22:53:49ID requested
12026-02-24 22:54:06announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Abdominal aortic aneurysm, Fibroblast, Nfkb1
Contact List
Yuehong Zheng
contact affiliationPeking Union Medical College Hospital
contact emailzhengyuehong2022@outlook.com
lab head
Yuehong Zheng
contact affiliationPeking Union Medical College Hospital
contact emailzhengyuehong2022@outlook.com
dataset submitter
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