⮝ Full datasets listing
PXD074835
PXD074835 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Thalassemia carrier screening in pregnant women based on targeted quantification of hemoglobin subunits by LC-MS/MS |
| Description | This study developed a novel thalassemia carrier screening method for pregnant women using LC-MS/MS-based targeted quantification of seven hemoglobin subunits. A machine learning model was trained on 1,726 subjects, achieving an AUC > 0.95. This approach provides a robust and physiologically adaptive strategy that outperforms traditional hematological indices in the pregnant population. |
| HostingRepository | iProX |
| AnnounceDate | 2026-02-17 |
| AnnouncementXML | Submission_2026-03-26_17:35:59.143.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yixi Cai |
| SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | QTRAP 6500 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-02-24 19:44:10 | ID requested | |
| ⏵ 1 | 2026-03-26 17:35:59 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: thalassemia, pregnant women, hemoglobin subunit, LC-MS/MS, machine learning |
Contact List
| Guixue Hou | |
|---|---|
| contact affiliation | University of Chinese Academy of Sciences |
| contact email | houguixue@genomics.cn |
| lab head | |
| Yixi Cai | |
| contact affiliation | University of Chinese Academy of Sciences |
| contact email | caiyixi@genomics.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
