⮝ Full datasets listing
PXD074832
PXD074832 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Given that ribokinase (RBKS) phosphorylates D-ribose, we performed proteomic analysis on Rbks-knockout mouse livers and identified 117 differentially expressed proteins primarily involved in glycolipid metabolism and oxidative phosphorylation |
| Description | Given that ribokinase (RBKS) catalyzes the key phosphorylation of D-ribose to ribose-5-phosphate, we hypothesized that the Rbks gene plays a critical role in regulating systemic glucose and lipid metabolism. To test this hypothesis, we generated Rbks-knockout (Rbks-KO) C57BL/6J mice using CRISPR/Cas9 technology and performed proteomic analysis on their livers. A total of 117 differentially expressed proteins were identified, which are primarily involved in glycolipid metabolism and oxidative phosphorylation. |
| HostingRepository | iProX |
| AnnounceDate | 2026-02-16 |
| AnnouncementXML | Submission_2026-02-24_19:37:08.458.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Houyu Li |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-02-24 19:36:44 | ID requested | |
| ⏵ 1 | 2026-02-24 19:37:08 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Rbks Knockout Mice, Liver |
Contact List
| Yan Su | |
|---|---|
| contact affiliation | Baotou Medical College |
| contact email | 101999104@btmc.edu.cn |
| lab head | |
| Houyu Li | |
| contact affiliation | Baotou Medical College |
| contact email | lihouyv18@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
