PXD074762

PXD074762 is an original dataset announced via ProteomeXchange.

Title	Candida auris co-cultured with bone marrow derived macrophages (BMDMs) in-vitro for 2hrs, followed by TMT based quantitative proteomics to identify differentially abundant proteins.
Description	The aim of this study was to elucidate the pathogenic mechanism of C. auris during its early phase interaction with host both in-vitro. To this end, we used a quantitative proteomics approach to determine the virulence factors modulating C. auris host-pathogen interaction. We utilized an experimental setup, utilizing an in-vitro co-culture of C. auris with murine macrophages. Following the infection for 2hrs with the immune cells, we applied a TMT based quantitative proteomics strategy to characterize the virulence repertoire of C. auris.
HostingRepository	PRIDE
AnnounceDate	2026-09-01
AnnouncementXML	Submission_2026-09-01_02:38:59.107.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Markus Hartl
SpeciesList	scientific name: [Candida] auris; NCBI TaxID: NEWT:498019;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-24 05:39:00	ID requested
⏵ 1	2026-09-01 02:38:59	announced

10.3390/JOF12090649;

submitter keyword: None

Rounik Mazumdar
contact affiliation	Medical University of Vienna, Spitalgasse 23, 1090 Wien
contact email	rounik.mazumdar@meduniwien.ac.at
lab head
Markus Hartl
contact affiliation	Max Perutz Labs, Mass Spectrometry Facility, Vienna Biocenter Campus (VBC), Dr. Bohr-Gasse 9, Vienna, Austria
contact email	proteomics@maxperutzlabs.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD074762

PRIDE project URI

• PRIDE
  1. PXD074762
     1. Label: PRIDE project
     2. Name: Candida auris co-cultured with bone marrow derived macrophages (BMDMs) in-vitro for 2hrs, followed by TMT based quantitative proteomics to identify differentially abundant proteins.