PXD074670

PXD074670 is an original dataset announced via ProteomeXchange.

Title	Proteomic Characterization of Polymicrobial Biofilms in Human Urine
Description	When Proteus mirabilis, Enterococcus faecalis, and Escherichia coli are co-cultured in human urine, they form biofilms with increased biomass. This increase in biomass is due to a rise in the total protein content of the biofilm rather than other components, such as carbohydrates or nucleic acids. The study focused on identifying proteins that are enriched in polymicrobial biofilms (co-cultures) compared to monomicrobial biofilms. Proteins that increase in relative abundance during co-culture may serve as targets for preventing the formation of recalcitrant polymicrobial biofilms.
HostingRepository	PRIDE
AnnounceDate	2026-08-24
AnnouncementXML	Submission_2026-08-23_16:10:30.283.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Min Ma
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: NEWT:562; scientific name: Enterococcus faecalis (Streptococcus faecalis); NCBI TaxID: NEWT:1351; scientific name: Proteus mirabilis HI4320; NCBI TaxID: NEWT:529507;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Astral

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-19 23:03:27	ID requested
⏵ 1	2026-08-23 16:10:31	announced

10.1016/j.bioflm.2026.100378;

Taddei SM, Deka N, Marin A, Hunt BC, Guterman LB, Ma M, Qu J, Armbruster CE, enhances polymicrobial interactions and antibiotic tolerance on urinary catheters. Biofilm, 12():100378(2026) [pubmed]

submitter keyword: proteomics, LC-MS, Enterococcus faecalis,Proteus mirabilis, biofilm, Escherichia coli

Jun Qu
contact affiliation	Department of Pharmaceutical Sciences, University at Buffalo, US
contact email	junqu@buffalo.edu
lab head
Min Ma
contact affiliation	University at Buffalo
contact email	minma@buffalo.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD074670

PRIDE project URI

• PRIDE
  1. PXD074670
     1. Label: PRIDE project
     2. Name: Proteomic Characterization of Polymicrobial Biofilms in Human Urine