PXD074520

PXD074520 is an original dataset announced via ProteomeXchange.

Title	Developmental programming of the murine gut ecosystem emerges from coordinated host–microbiome maturation: a longiutudinal controlled study
Description	Early-life development of the gut microbiome plays a critical role in shaping host physiology, yet how microbial community assembly, functional capacity, and host intestinal maturation are coordinated over time remains incompletely understood. Most studies rely on cross-sectional sampling or limited functional resolution, constraining insight into developmental dynamics. Here, we aimed to characterize gut ecosystem maturation across early life using longitudinal, metaproteome-level analysis in a controlled murine model.
HostingRepository	PRIDE
AnnounceDate	2026-09-07
AnnouncementXML	Submission_2026-09-07_05:11:32.874.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Giacomo Carta
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-16 07:31:33	ID requested
⏵ 1	2026-09-07 05:11:33	announced

10.1186/S40168-026-02541-3;

submitter keyword: Gut microbiome development

Host-microbiome interactions

Diet

Metaproteomics

Manuela Schmidt
contact affiliation	Division of Pharmacology and Toxicology, Department of Pharmaceutical Sciences, University of Vienna
contact email	manuela_schmidt@univie.ac.at
lab head
Giacomo Carta
contact affiliation	Systems Biology of Pain Laboratory, Division of Pharmacology & Toxicology, Department of Pharmaceutical Sciences, University of Vienna
contact email	giacomo.carta@univie.ac.at
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/09/PXD074520

PRIDE project URI

• PRIDE
  1. PXD074520
     1. Label: PRIDE project
     2. Name: Developmental programming of the murine gut ecosystem emerges from coordinated host–microbiome maturation: a longiutudinal controlled study