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PXD074428

PXD074428 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDepletion-Free Automated Enrichment of Plasma Glycopeptides for High-Throughput and Comprehensive Glycoproteomic Profiling
DescriptionWe developed 3kMAX, a depletion-free and fully automated N-glycopeptide enrichment platform combining 3 kDa MWCO filtration and positive-pressure MAX enrichment in a 96-well format. It processes up to 96 serum samples with minimal hands-on time and improves glycopeptide selectivity, identification depth, and quantitative reproducibility. Benchmarking confirmed robust, unbiased performance across inputs and throughputs. Applied to hepatocellular carcinoma serum, 3kMAX enabled high-throughput site-specific glycoproteomics and revealed disease-associated glycosylation remodeling.
HostingRepositoryMassIVE
AnnounceDate2026-02-14
AnnouncementXMLSubmission_2026-02-14_00:02:43.178.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJung Hoon Choi
SpeciesList scientific name: human;
ModificationListunknown modification
InstrumentOrbitrap Astral Zoom
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-02-13 05:31:00ID requested
12026-02-14 00:02:43announced
Publication List
no publication
Keyword List
submitter keyword: automauted glycopeptide enrichment, depletion-free, high-throughput glycoproteomics, increased glycopeptide identification, plasma glycoproteomics, DatasetType:Proteomics
Contact List
Jin Young Kim
contact affiliationKorea Basic Science Institute
contact emailjinyoung@kbsi.re.kr
lab head
Jung Hoon Choi
contact affiliationKBSI
contact emailjhchoi19@kbsi.re.kr
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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