PXD074343

PXD074343 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomic profiling of ruptured and unruptured brain arteriovenous malformations
Description	This study presents a quantitative proteomic analysis of human brain arteriovenous malformation (AVM) tissues with different rupture status. Surgically resected AVM specimens from ruptured and unruptured lesions were subjected to protein extraction, enzymatic digestion, and liquid chromatography–tandem mass spectrometry (LC-MS/MS) analysis. The dataset aims to characterize proteomic alterations associated with hemorrhagic presentation and to identify molecular pathways potentially involved in vascular instability. Raw mass spectrometry data and processed identification results are provided to facilitate data reuse and integrative multi-omics analyses.
HostingRepository	PRIDE
AnnounceDate	2026-02-15
AnnouncementXML	Submission_2026-02-14_17:13:44.103.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wei Zhu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	EASY-nLC 1200

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-11 06:59:59	ID requested
⏵ 1	2026-02-14 17:13:44	announced

Dataset with its publication pending

submitter keyword: proteomics, rupture status, vascular biology,Brain arteriovenous malformation, LC-MS/MS

Wei Zhu
contact affiliation	Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University
contact email	drzhuwei@fdu.edu.cn
lab head
Wei Zhu
contact affiliation	Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University
contact email	drzhuwei@fudan.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD074343

PRIDE project URI

• PRIDE
  1. PXD074343
     1. Label: PRIDE project
     2. Name: Quantitative proteomic profiling of ruptured and unruptured brain arteriovenous malformations