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PXD074220

PXD074220 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAnalysis of rat plasma proteome using Label Free whole proteomics technology
DescriptionIn this study, a proteomic strategy was employed to explore the potential mechanisms through which CS and PCS exert therapeutic effects against POI. The results indicated that both CS and PCS might alleviate POI by regulating the MAPK signaling pathway. These compounds could delay or reverse the progression of POI by activating metabolic-related pathways, such as AMPK, promoting the synthesis of antioxidant substances, inhibiting the release of inflammatory factors, and coordinating ribosomal function with anti-apoptotic signaling to maintain metabolic and functional homeostasis in ovarian cells. Core proteins, including P63245, P10719, and P04636, may serve as key therapeutic targets for these effects.
HostingRepositoryiProX
AnnounceDate2026-02-08
AnnouncementXMLSubmission_2026-08-13_20:05:19.996.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYing Zhang
SpeciesList scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Exploris 240
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-02-08 23:15:54ID requested
⏵ 12026-08-13 20:05:20announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Plasma, Proteome profiling, Biomarker
Contact List
Kunming Qin
contact affiliationJiangsu Ocean University
contact emailqinkm123@126.com
lab head
Ying Zhang
contact affiliationJiangsu Ocean University
contact email2245246448@qq.com
dataset submitter
Full Dataset Link List
iProX dataset URI

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