PXD074147

PXD074147 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	BioID-MS identification of WDR62 binding partners.
Description	To identify novel WDR62 binding partners, we generated WDR62 fusion proteins tagged with the BirA* promiscuous biotin ligase. This allowed for spatially restricted biotin labelling, affinity isolation, and detection of proximal proteins and transient interactors within an approximate 10 nm radius of WDR62 through affinity isolation and identificaiton by mass spectrometry.
HostingRepository	PRIDE
AnnounceDate	2026-04-06
AnnouncementXML	Submission_2026-04-05_16:11:00.631.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dominic Ng
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	biotinylated residue
Instrument	TripleTOF 5600

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-02-06 05:24:38	ID requested
⏵ 1	2026-04-05 16:11:02	announced

Publication List

Morris MJ, Yeap YY, Edwards JR, Chen C, Paolino A, Furness SGB, Millard SS, Pagan JK, Fenlon LR, Ng DCH, Microcephaly-associated protein WDR62 supports purine metabolism by interacting with co-chaperone BAG2. EMBO J, 45(7):2157-2181(2026) [pubmed]
10.1038/s44318-026-00724-0;

Morris MJ, Yeap YY, Edwards JR, Chen C, Paolino A, Furness SGB, Millard SS, Pagan JK, Fenlon LR, Ng DCH, Microcephaly-associated protein WDR62 supports purine metabolism by interacting with co-chaperone BAG2. EMBO J, 45(7):2157-2181(2026) [pubmed]

10.1038/s44318-026-00724-0;

Keyword List

submitter keyword: interphase. BioID, mitosis,WDR62

submitter keyword: interphase. BioID, mitosis,WDR62

Contact List

Dominic Chi Hiung Ng
contact affiliation	The University of Queensland
contact email	d.ng1@uq.edu.au
lab head
Dominic Ng
contact affiliation	The University of Queensland
contact email	d.ng1@uq.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD074147
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD074147

PRIDE project URI

Repository Record List

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