PXD073941 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mycobacterium tuberculosis VadK required for regulation of the methylcitrate cycle and virulence |
| Description | We performed co-immunoprecipitation experiments using WT Mtb transformed with a plasmid encoding a FLAG-tagged VadK under a constitutive promoter (VadKMtb). We immunoprecipitated from whole cell lysates of WT and VadKMtb grown in standard 7H9 media with and without propionate to identify interactions that are important during growth in propionate. By applying a stringent cut-off to filter out nonspecific binding (proteins with peptide spectrum matches (PSMs) of each replicate ≤1 in the WT control and ≥50 in VadKMtb). |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-19 |
| AnnouncementXML | Submission_2026-03-19_07:35:55.223.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Tom Mendum |
| SpeciesList | scientific name: Mycobacterium tuberculosis H37Rv; NCBI TaxID: NEWT:83332; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Fusion Lumos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-02-02 13:26:06 | ID requested | |
| ⏵ 1 | 2026-03-19 07:35:55 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: metabolism, virulence,Mycobacterium tuberculosis, regualtion, kinase |
Contact List
| Dany Beste |
|---|
| contact affiliation | University of Surrey |
| contact email | d.beste@surrey.ac.uk |
| lab head | |
| Tom Mendum |
|---|
| contact affiliation | University of Surrey |
| contact email | t.mendum@surrey.ac.uk |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD073941 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD073941
- Label: PRIDE project
- Name: Mycobacterium tuberculosis VadK required for regulation of the methylcitrate cycle and virulence
