⮝ Full datasets listing
PXD073865
PXD073865 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SEC-MS characterization of KOLF2 neuronal and cardiomyocyte differentiation - CM4AI |
| Description | Description: This dataset contains mass spectrometry-based proteomics data investigating the protein-protein interaction networks during the differentiation of KOLF2.1J human induced pluripotent stem cells (iPSCs). We employed Size Exclusion Chromatography coupled with Mass Spectrometry (SEC-MS) to map multiscale biological organization across three distinct stages: Parental: Undifferentiated iPSCs. NPC: Neural Progenitor Cells. Neurons: Terminally differentiated neurons. Cardio: Terminally differentiated Cardiomyocyte. The study aims to identify how protein complexes and networks are reorganized during neuronal lineage commitment and cardiomycyte differentiation. Data was acquired on a Bruker timsTOF platform, and quantitative analysis was performed using Spectronaut. Experimental Design: Sample Groups: Parental (Reps 1-4), NPC (Reps 1-2), Neuron (Reps 1-3), and Cardio (Reps 1-2). Modality: SEC-MS for protein correlation profiling. Data Processing: Raw data was processed using Spectronaut; downstream analysis was conducted in R using MSstats-compatible formats. |
| HostingRepository | MassIVE |
| AnnounceDate | 2026-05-19 |
| AnnouncementXML | Submission_2026-05-19_11:31:42.432.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Antoine Forget |
| SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro 2 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-01-30 14:06:54 | ID requested | |
| ⏵ 1 | 2026-05-19 11:31:42 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: KOLF2, IPSC, SEC-MS, Neuron, Cardiomyocyte, DatasetType:Proteomics |
Contact List
| Nevan J. Krogan | |
|---|---|
| contact affiliation | University of California, San Francisco |
| contact email | nevan.krogan@ucsf.edu |
| lab head | |
| Antoine Forget | |
| contact affiliation | UCSF |
| contact email | antoine.forget@ucsf.edu |
| lab head | |
| Antoine Forget | |
| contact affiliation | UCSF |
| contact email | antoine.forget@ucsf.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v12/MSV000100676/ |
