PXD073775

PXD073775 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Global analysis of cancer cell responses to USP9X inhibition
Description	K-GG ubiquitin profiling of SK-MEL-2 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). Sample IDs: #31-35 Control 30 min SK-MEL-2 #36-40 WEHI-092 30 min SK-MEL-2 #41-45 Control 360 min SK-MEL-2 #46-50 WEHI-092 360 min SK-MEL-2 #51-55 Control 24 h SK-MEL-2 #56-60 WEHI-092 24 h SK-MEL-2
HostingRepository	PRIDE
AnnounceDate	2026-04-09
AnnouncementXML	Submission_2026-04-09_06:56:00.443.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Philipp Schenk
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	ubiquitinylated lysine
Instrument	Orbitrap Astral

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2026-01-29 05:57:54	ID requested
⏵ 1	2026-04-09 06:56:01	announced

Publication List

10.1038/s44318-026-00742-y;
Schenk P, Devine SM, Cobbold SA, Geoghegan ND, Kyran EL, Ang CS, Alexandrovics JA, Calleja DJ, Multari DH, Vaibhav V, Lu BGC, Klemm TA, Dagley LF, Lowes KN, Williamson NA, Eichhorn PJA, Ng AP, Feltham R, Komander D, Global analysis of cancer cell responses to USP9X inhibition. EMBO J, 45(9):3306-3331(2026) [pubmed]

10.1038/s44318-026-00742-y;

Schenk P, Devine SM, Cobbold SA, Geoghegan ND, Kyran EL, Ang CS, Alexandrovics JA, Calleja DJ, Multari DH, Vaibhav V, Lu BGC, Klemm TA, Dagley LF, Lowes KN, Williamson NA, Eichhorn PJA, Ng AP, Feltham R, Komander D, Global analysis of cancer cell responses to USP9X inhibition. EMBO J, 45(9):3306-3331(2026) [pubmed]

Keyword List

submitter keyword: None

submitter keyword: None

Contact List

David Komander
contact affiliation	WEHI
contact email	dk@wehi.edu.au
lab head
Philipp Schenk
contact affiliation	WEHI
contact email	schenk.p@wehi.edu.au
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD073775
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD073775

PRIDE project URI

Repository Record List

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