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PXD073445

PXD073445 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInduction of senescence in a translational cell model for testicular cells by Bleomycin treatment.
DescriptionWe aimed to establish a translational aging model of testicular peritubular cells (TPCs), which is based on immortalized nonhuman primate (NHP) peritubular cells (iMKTPCs) from Callithrix jacchus. Cellular senescence was robustly induced within 10 days by exposure to 25 µg/ml bleomycin for 24 h.
HostingRepositoryPRIDE
AnnounceDate2026-05-13
AnnouncementXMLSubmission_2026-05-13_09:42:08.393.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterThomas Fröhlich
SpeciesList scientific name: Callithrix jacchus; NCBI TaxID: NEWT:9483;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF-X
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-23 03:30:51ID requested
12026-05-13 09:42:08announced
Publication List
10.1007/S00418-026-02489-3;
Keyword List
submitter keyword: translational model, peritubular cells
senescence,testis
Contact List
Thomas Fröhlich
contact affiliationGene Center Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 D-81377 München
contact emailfrohlich@genzentrum.lmu.de
lab head
Thomas Fröhlich
contact affiliationLudwig-Maximilians-Universität München Genzentrum Laboratory for Functional Genome Analysis Feodor-Lynen-Str. 25 81377 Munich
contact emailfrohlich@genzentrum.lmu.de
dataset submitter
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Dataset FTP location
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