⮝ Full datasets listing
PXD073397
PXD073397 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | SC-43 Inhibits Methicillin-resistant Staphylococcus aureus Through Inhibition of Heme Biosynthesis |
| Description | SC-43 inhibits the key enzyme coproporphyrin ferrochelatase (CpfC) of the coproporphyrin-dependent (CPD) heme synthesis pathway and interferes with the bacterial porphyrin metabolism. |
| HostingRepository | iProX |
| AnnounceDate | 2026-01-22 |
| AnnouncementXML | Submission_2026-05-26_01:32:11.687.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Wei Huang |
| SpeciesList | scientific name: Staphylococcus aureus; NCBI TaxID: 1280; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF-X |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-01-22 00:24:14 | ID requested | |
| 1 | 2026-03-20 02:23:25 | announced | |
| ⏵ 2 | 2026-05-26 01:32:12 | announced | 2026-05-26: Add info |
Publication List
| Huang Y, Ye Y, Zhu X, Liang D, Cui R, Yuan X, Li X, Zou Q, Li H, Huang W, SHP-1 agonist SC-43 limits methicillin-resistant Staphylococcus aureus infection through inhibition of heme biosynthesis. EMBO Mol Med, 18(5):1990-2005(2026) [pubmed] |
Keyword List
| submitter keyword: SC-43, MRSA, heme |
Contact List
| Wei Huang | |
|---|---|
| contact affiliation | Shenzhen People's Hospital |
| contact email | screening_sz@163.com |
| lab head | |
| Wei Huang | |
| contact affiliation | Shenzhen People's Hospital |
| contact email | screening_sz@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
