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PXD073249

PXD073249 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSystematic Quantification of Protein O-GlcNAcylation Reveals Common and Cell-Type-Specific Responses to N-Glycosylation Inhibition in Human Cells
DescriptionIn this work, we systematically and site-specifically analyzed protein O-GlcNAcylation under the N-glycosylation inhibition through the integration of metabolic labeling, bio-orthogonal chemistry, and multiplexed proteomics. The experiments were performed in three types of human cells, i.e., HEK293T, HepG2, and Jurkat cells.
HostingRepositoryPRIDE
AnnounceDate2026-06-11
AnnouncementXMLSubmission_2026-06-11_03:10:02.505.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterLongping Fu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListcomplex glycosylation
InstrumentOrbitrap Eclipse
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-19 13:04:46ID requested
12026-06-11 03:10:03announced
Publication List
10.1021/acs.analchem.6c00972;
Fu L, Yin K, Xu X, Wu R, Systematic Quantification of Protein O-GlcNAcylation Reveals Common and Cell-Type-Specific Responses to N-Glycosylation Inhibition in Human Cells. Anal Chem, 98(21):15689-15699(2026) [pubmed]
Keyword List
submitter keyword: Glycoproteomics,protein O-GlcNAcylation
Contact List
Ronghu Wu
contact affiliationChemistry & Biochemistry
contact emailronghu.wu@chemistry.gatech.edu
lab head
Longping Fu
contact affiliationGeorgia Institute of Technology
contact emaillpfu46@gatech.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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