PXD073166 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis of SIRT1-interacting proteins in rat nucleus pulposus cells |
| Description | This study identifies proteins interacting with SIRT1 in nucleus pulposus cells. We performed a pulldown assay using anti-SIRT1 antibodies. The analysis identified 540 unique SIRT1-binding partners. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-27 |
| AnnouncementXML | Submission_2026-04-26_16:14:35.715.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | QIQI XIE |
| SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: NEWT:10116; |
| ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2026-01-16 05:16:43 | ID requested | |
| ⏵ 1 | 2026-04-26 16:14:36 | announced | |
Publication List
| 10.1111/acel.70449; |
| Wu ZL, Ran R, Xie QQ, Zhang C, Chen YJ, Cheng P, Wang KP, Zhang HH, FGF21-Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO3. Aging Cell, 25(4):e70449(2026) [pubmed] |
Keyword List
| submitter keyword: Nucleus pulposus cells, Proteomics,SIRT1, Co-immunoprecipitation |
Contact List
| Haihong Zhang |
|---|
| contact affiliation | Second Hospital of Lanzhou University |
| contact email | jieqiqi0429@gamil.com |
| lab head | |
| QIQI XIE |
|---|
| contact affiliation | University of Illinois Urbana-Champaign |
| contact email | jieqiqi0429@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD073166 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD073166
- Label: PRIDE project
- Name: Proteomic analysis of SIRT1-interacting proteins in rat nucleus pulposus cells
