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PXD073151

PXD073151 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCASKIN1 Triggers Granulosa Cell Apoptosis via FOXO1-Mediated Mitochondrial Dysfunction
DescriptionIn our study, CASKIN1 was highly expressed in granulosa cells of ovaries from aged mice. We subsequently demonstrated that CASKIN1 induces oxidative stress and mitochondrial dysfunction, thereby promoting granulosa cell apoptosis by enhancing nuclear expression of FOXO1.
HostingRepositoryiProX
AnnounceDate2026-01-16
AnnouncementXMLSubmission_2026-01-15_22:42:53.489.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterShunran Zhao
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-15 22:42:35ID requested
12026-01-15 22:42:54announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Ovarian aging, granulosa cells, mitochondrial function, CASKIN1, apoptosis
Contact List
Shunran Zhao
contact affiliationHebei Agricultural University , College of Animal Science and Technology
contact emailzhaoshunran9@163.com
lab head
Shunran Zhao
contact affiliationHebei Agricultural University
contact emailzhaoshunran9@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI