PXD073051

PXD073051 is an original dataset announced via ProteomeXchange.

Title	Spatial proteomics based on laser capture micro-dissection (LCM) for investigating the impact of CD168+ TAM- coated tumor region (CCTR) on CD8+ T cells Function in colon cancer tissues
Description	Multiplex immunofluorescence staining for CD11b, CD168, CD8, and Pan-CK was performed on three colon cancer specimens to identify CCTR regions. Subsequently, CD8+ T cells located at varying distances from the CCTR were subjected to single-cell resolution laser capture micro-dissection (LCM) and spatial proteomics analysis. These cells were categorized into three groups: the CCTR group (≤50 μm, n=393), the ad-CCTR group (>50 μm and ≤200 μm, n=375), and the non-CCTR group (>200 μm, n=383).
HostingRepository	iProX
AnnounceDate	2026-01-14
AnnouncementXML	Submission_2026-01-14_00:30:50.880.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhihao Wei
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	timsTOF Pro

Revision	Datetime	Status	ChangeLog Entry
0	2026-01-14 00:30:32	ID requested
⏵ 1	2026-01-14 00:30:51	announced

Dataset with its publication pending

submitter keyword: Spatial proteomics, laser capture micro-dissection (LCM), CD168+ TAM- coated tumor region (CCTR), CD8+ T cells

Jianjun Li
contact affiliation	Southwest Hosipital, Third Military Medical University
contact email	jianjunli@tmmu.edu.cn
lab head
Zhihao Wei
contact affiliation	Southwest Hosipital, Third Military Medical University
contact email	weizhihao7768@tmmu.edu.cn
dataset submitter

iProX dataset URI