⮝ Full datasets listing
PXD072975
PXD072975 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Triglyceride induces endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity |
| Description | Triglyceride synthesis promotes the activation of C-type lectin receptors signaling pathway upon fungal infection. Triglyceride synthesis induces endoplasmic reticulum lipid bilayer stress and activates the PERK kinase after fungal stimulation. PERK mediates autophagic degradation of SHP-1 to amplify the SYK-associated antifungal signaling. |
| HostingRepository | iProX |
| AnnounceDate | 2026-01-12 |
| AnnouncementXML | Submission_2026-01-12_17:29:55.925.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Han Wu |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2026-01-12 17:29:19 | ID requested | |
| ⏵ 1 | 2026-01-12 17:29:56 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Antifungal immunity, Triglycerides, PERK, Lipid bilayer stress, Drug target |
Contact List
| Chengjiang Gao | |
|---|---|
| contact affiliation | School of Biomedical Sciences, Shandong University |
| contact email | cgao@sdu.edu.cn |
| lab head | |
| Han Wu | |
| contact affiliation | School of Biomedical Sciences, Shandong University |
| contact email | 986080632@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
