PXD072881

PXD072881 is an original dataset announced via ProteomeXchange.

Title	Proteomic of rabbit fumer defects renconstructed by 4D metamaterials
Description	4D printing, integrating the temporal dimension into 3D printing, offers transformative potential for bone implants. Yet its application to metallic materials is constrained by the scarcity of suitable alloys and the requirement for harsh external stimuli to trigger shape change. Here, we introduce 4D printed metallic metamaterials (4DMM) driven by controlled biodegradation. The 4DMM combine biodegradable constraints (e.g., Mg or Zn) with biometals of higher corrosion potential (e.g., Ti). Upon electrochemical degradation of the constraint, the metamaterials recover their original geometry—via stretching, bending, or expansion—generating programmable recoil forces tuned through structural design parameters. When developed as scaffolds for bone implants, 4DMM exhibit excellent cytocompatibility and, in vivo, promote superior bone regeneration through the synergistic effects of bioactivity and mechanical stimulation. This strategy establishes a new paradigm in 4D metal printing via metamaterial design, enabling bioactive, self-restoring implants with broad applicability across biomedical engineering.
HostingRepository	PRIDE
AnnounceDate	2026-05-04
AnnouncementXML	Submission_2026-05-04_01:12:43.548.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yu Qin
SpeciesList	scientific name: Oryctolagus cuniculus (Rabbit); NCBI TaxID: NEWT:9986;
ModificationList	acetylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2026-01-10 06:36:57	ID requested
⏵ 1	2026-05-04 01:12:44	announced

Dataset with its publication pending

submitter keyword: Bone implants

4D printing

Yu Qin
contact affiliation	Peking University
contact email	qin_y@pku.edu.cn
lab head
Yu Qin
contact affiliation	Peking University
contact email	qin_y@pku.edu.cn
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD072881
     1. Label: PRIDE project
     2. Name: Proteomic of rabbit fumer defects renconstructed by 4D metamaterials