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PXD072636

PXD072636 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePSM alleviates ulcerative colitis by modulating gut microbiota
DescriptionPSM exhibited various biological activities, such as anti-inflammation, anticancer and antiviral, but its effects on lipid profile have not been extensively investigated. In the present study, we found PSM treatment can effectively ameliorate colitis and improve lipid profile including reduced FA uptake and induced DNL. Interestingly, recent studies revealed certain compound with poor intestinal absorption exert remarkable therapeutic effects through modulating gut microbiome. PSM also exhibits remarkable effects on the composition of gut microbiota, characterized by increasing the ratio of Firmicutes and Bacteroidota at the phylum level.
HostingRepositoryiProX
AnnounceDate2026-01-04
AnnouncementXMLSubmission_2026-08-13_20:01:39.681.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYan Cheng
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive Plus
Dataset History
RevisionDatetimeStatusChangeLog Entry
02026-01-05 00:52:59ID requested
12026-08-13 20:01:40announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Ulcerative colitis, lipid dysmeatbolism, gut microbiota
Contact List
Weifeng Zhu
contact affiliationJiangxi University of Chinese Medicine
contact email19930220@jxutcm.edu.cn
lab head
Yan Cheng
contact affiliationJiangxi University of Chinese Medicine
contact emailchengyan_8304@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI