PXD072342 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mass spectrometry-based proteomic characterization of TgGCN5b, TgPHD1, TgPZP1, TgGNAT1 and TgGNAT2 interactomes |
| Description | Histone acetylation, a fundamental epigenetic mechanism that controls gene activity, is essential for the developmental plasticity and virulence of the parasite Toxoplasma gondii. However, how this parasite organizes and deploys its acetyltransferase machinery has remained unclear. Here, we show that T. gondii rewired this process using a plant-like system built around the acetyltransferase TgGCN5b, which differs from the typical SAGA complex found in other eukaryotes. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-07-25 |
| AnnouncementXML | Submission_2026-07-25_06:45:37.110.xml |
| DigitalObjectIdentifier | https://doi.org/10.6019/PXD072342 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Yohann Couté |
| SpeciesList | scientific name: Toxoplasma gondii RH; NCBI TaxID: NEWT:383379; scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Exploris 480; Orbitrap Ascend |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-12-23 00:06:26 | ID requested | |
| ⏵ 1 | 2026-07-25 06:45:37 | announced | |
Publication List
Keyword List
| submitter keyword: SAGA,Toxoplasma gondii, histone acetylation, gene expression, epigenetic |
Contact List
| Yohann Couté |
|---|
| contact affiliation | EDyP |
| contact email | yohann.coute@cea.fr |
| lab head | |
| Yohann Couté |
|---|
| contact affiliation | EDyP |
| contact email | yohann.coute@cea.fr |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/07/PXD072342 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD072342
- Label: PRIDE project
- Name: Mass spectrometry-based proteomic characterization of TgGCN5b, TgPHD1, TgPZP1, TgGNAT1 and TgGNAT2 interactomes
