⮝ Full datasets listing
PXD072280
PXD072280 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A Peptide Immunomodulator Potentiates Regulatory T Cells via MST1 Kinase Activation to Promote Immune Tolerance in Mice and Humanized Models |
| Description | To systematically decode the functional motifs within proteins in Tregs, we focused on their intrinsically disordered regions (IDRs), which are enriched in post-translational modification (PTM) sites that act as molecular switches for Treg stability and function. We built upon a prior methodology to employ a modified N-gram model for analyzing IDR sequences and computationally designing a library of novel oligopeptides. |
| HostingRepository | iProX |
| AnnounceDate | 2025-12-21 |
| AnnouncementXML | Submission_2025-12-22_00:33:41.347.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yu Wang |
| SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | timsTOF Pro |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-12-22 00:33:03 | ID requested | |
| ⏵ 1 | 2025-12-22 00:33:41 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: treg, immune tolerance, oligopeptide |
Contact List
| Yao Sun | |
|---|---|
| contact affiliation | School & Hospital of Stomatology, Tongji University |
| contact email | yaosun@tongji.edu.cn |
| lab head | |
| Yu Wang | |
| contact affiliation | School & Hospital of Stomatology, Tongji University |
| contact email | yu_wang2022@tongji.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
