PXD072207

PXD072207 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Proteomics of Extracellular Vesicles from hiPSC-Derived Cardiac Organoids
Description	Human cardiac organoids were derived from hiPSCs using a regimen of small molecules and morphogens. Extracellular vesicles (cardEVs) were subsequently isolated from the conditioned medium via differential centrifugation. Finally, the proteomic cargo of cardEVs was characterized using LC-MS/MS and bioinformatically compared against EVs derived from the AC10 cardiomyocyte cell line and cadaveric human heart explants (heEVs).
HostingRepository	PRIDE
AnnounceDate	2026-02-02
AnnouncementXML	Submission_2026-02-01_16:14:30.106.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD072207
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Rune Matthiesen
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-12-19 07:11:17	ID requested
⏵ 1	2026-02-01 16:14:31	announced

Publication List

10.3390/ijms27020981;
10.6019/PXD072207;
Vital CM, In, á, cio JM, Carvalho AS, Beck HC, Matthiesen R, Belo JA, Integrative Proteomics of Extracellular Vesicles from hiPSC-Derived Cardiac Organoids Reveals Heart Tissue-like Molecular Representativity. Int J Mol Sci, 27(2):(2026) [pubmed]

10.3390/ijms27020981;

10.6019/PXD072207;

Vital CM, In, á, cio JM, Carvalho AS, Beck HC, Matthiesen R, Belo JA, Integrative Proteomics of Extracellular Vesicles from hiPSC-Derived Cardiac Organoids Reveals Heart Tissue-like Molecular Representativity. Int J Mol Sci, 27(2):(2026) [pubmed]

Keyword List

submitter keyword: cardiod, Extracellular Vesicles, human,Cardiac Organoids

submitter keyword: cardiod, Extracellular Vesicles, human,Cardiac Organoids

Contact List

Rune Matthiesen
contact affiliation	iNOVA4Health, NOVA Medical School-Research, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Campo dos Mártires da Pátria, 130, 1169-056 Lisboa, Portugal
contact email	runem2009@gmail.com
lab head
Rune Matthiesen
contact affiliation	Computational and Experimental Biology Group, CEDOC NOVA MEDICAL SCHOOL / FACULDADE DE CIÊNCIAS MÉDICAS UNIVERSIDADE NOVA DE LISBOA Rua Câmara Pestana, 6-6A \| 1150-082 Lisboa Portugal
contact email	runem2009@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD072207
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/02/PXD072207

PRIDE project URI

Repository Record List

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