PXD072134

PXD072134 is an original dataset announced via ProteomeXchange.

Title	Serum proteome of the Egyptian rousette bat (Rousettus aegyptiacus) reveals signatures of immunity, proteostasis, and metabolism
Description	Bats are increasingly studied for their ability to coexist with diverse viruses of human health importance. While this focus has yielded insights into host–pathogen dynamics, baseline physiological data from healthy bats remain limited, constraining comparative and mechanistic understanding. Serum proteomics offers a direct window into circulating proteins that underpin immune regulation, cellular maintenance, and metabolism. Here, we characterize the serum proteome of healthy, captive Egyptian rousette bats (Rousettus aegyptiacus). Using untargeted proteomic profiling, we identified and ranked abundant proteins across major functional categories. This work provides the first-look of the Egyptian rousette bat serum proteome, providing a reference point for cross-species comparisons and future studies of bat immunity, metabolism, and longevity.
HostingRepository	PRIDE
AnnounceDate	2026-06-08
AnnouncementXML	Submission_2026-06-07_16:39:05.489.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Brooke Genovese
SpeciesList	scientific name: Rousettus aegyptiacus (Egyptian rousette) (Egyptian fruit bat); NCBI TaxID: NEWT:9407;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2025-12-18 00:47:03	ID requested
⏵ 1	2026-06-07 16:39:06	announced

10.1038/s41598-026-46577-9;

Genovese BN, Randhawa N, Neely BA, Grigorean G, Schuh AJ, Amman BR, Elbert JA, Anthony SJ, Mazet JAK, Towner JS, Bird BH, and metabolism. Sci Rep, 16(1):(2026) [pubmed]

submitter keyword: None

Brian H.
contact affiliation	Lab Director, One Health Institute Laboratory
contact email	bhbird@ucdavis.edu
lab head
Brooke Genovese
contact affiliation	Universiy of California, Davis - One Health Institute
contact email	brookegenovese94@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD072134

PRIDE project URI

• PRIDE
  1. PXD072134
     1. Label: PRIDE project
     2. Name: Serum proteome of the Egyptian rousette bat (Rousettus aegyptiacus) reveals signatures of immunity, proteostasis, and metabolism