PXD071947 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LC–MS/MS Proteomic Profiling of PEAK3 S69 Phosphorylation in PEAK3 Mutants |
| Description | This project aims to investigate how different PEAK3 mutations affect phosphorylation at serine 69 (S69). To this end, we performed proteomic analyses on immunoprecipitated (IP) PEAK3 samples from both wild-type and mutant constructs. Peptides containing phosphorylated and non-phosphorylated S69 were specifically identified and compared to assess mutation-dependent changes in S69 phosphorylation. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-16 |
| AnnouncementXML | Submission_2026-03-16_09:37:38.298.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Changyuan Hu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | phosphorylated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-12-13 05:29:06 | ID requested | |
| ⏵ 1 | 2026-03-16 09:37:39 | announced | |
Publication List
| 10.1016/j.jbc.2026.111365; |
| Zhao T, Hou J, Hu C, Cotton TR, Daly RJ, A tandem recruitment site in the pseudokinase scaffold PEAK3 is subject to phosphorylation-dependent regulation and cancer-associated mutations. J Biol Chem, ():111365(2026) [pubmed] |
Keyword List
| submitter keyword: proteomics, PEAK3,breast cancer, LC-MS/MS |
Contact List
| Roger J. Daly |
|---|
| contact affiliation | Cancer Program, Biomedicine Discovery Institute, Monash University, Clayton, Australia. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia. |
| contact email | roger.daly@monash.edu |
| lab head | |
| Changyuan Hu |
|---|
| contact affiliation | Monash University |
| contact email | changyuan.hu@monash.edu |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/03/PXD071947 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD071947
- Label: PRIDE project
- Name: LC–MS/MS Proteomic Profiling of PEAK3 S69 Phosphorylation in PEAK3 Mutants
