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PXD071659

PXD071659 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAutomatic Blood Protein Enrichment by Magnetic-COFs Polymers
DescriptionWe designed a platform to integrate magnetic COFs-based protein capture with scalable robotic handling, enabling high-throughput blood proteome profiling with more than 4,000 plasma proteins identified steadily for 30 samples per day. By combining molecular selectivity, magnetic enrichment, and automation, our strategy addresses key limitations in current blood proteomics workflows and offers a flexible foundation for the research of discovery proteomics from pancreatic ductal adenocarcinoma patients.
HostingRepositoryPRIDE
AnnounceDate2026-04-10
AnnouncementXMLSubmission_2026-04-09_22:55:24.200.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYuanyu Huang
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationListiodoacetamide derivatized residue
InstrumenttimsTOF HT
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-05 17:35:08ID requested
12026-04-09 22:55:24announced
Publication List
10.1021/ACS.ANALCHEM.5C08111;
Keyword List
submitter keyword: Mass Spectrometry, Automatic Protocol, Pancreatic Ductal Adenocarcinoma, Peptide Identification,Blood Proteome, Covalent Organic Frameworks (COFs), Cancer Proteins
Contact List
Hui Zhang
contact affiliationDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States
contact emailhuizhang@jhu.edu
lab head
Yuanyu Huang
contact affiliationJohns Hopkins University
contact emailyhuan295@jh.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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