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PXD071493

PXD071493 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleFirst insight into the regulatory role of the glycoprotein hormones GPA2 and GPB5 in the small-spotted catshark (Scyliorhinus canicula L.) during spermiogenesis
DescriptionThis study is the first to report the effects of stimulation with recombinant ScGPA2, ScGPB5, and single-chain ScGPB5#ScGPA2 on vertebrate testicular tissue in vitro. A large-scale, untargeted proteomic analysis revealed for the first time that all three—ScGPA2, ScGPB5, and single-chain ScGPB5#ScGPA2—can modulate the abundance of 103 of the 7,619 identified proteins, including proteins related to spermiogenesis and immunity, as well as others that are less well characterized.
HostingRepositoryiProX
AnnounceDate2025-12-03
AnnouncementXMLSubmission_2025-12-02_17:55:55.045.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterBenoit Bernay
SpeciesList scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-02 17:55:17ID requested
12025-12-02 17:55:55announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: GPA2, GPB5, thyrostimulin, Spermiogenesis, Chondrichthyes, Elasmobranchs
Contact List
Sourdaine Pascal
contact affiliationUR MERSEA Université de Caen Normandie
contact emailpascal.sourdaine@unicaen.fr
lab head
Benoit Bernay
contact affiliationPlateforme Proteogen, Université de Caen Normandie
contact emailbenoit.bernay@unicaen.fr
dataset submitter
Full Dataset Link List
iProX dataset URI