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PXD071470

PXD071470 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComplete post-transcriptional modification profiles in individual Staphylococcus aureus tRNA species
DescriptionTransfer RNAs play a critical role in protein synthesis by matching mRNA codons to their corresponding amino acids. Their post-transcriptional modifications, which modulate structure, stability, and codon decoding properties, are now recognized as key regulators of translation and cellular adaptation across diverse organisms, including bacterial pathogens. Here, we provide a comprehensive analysis of tRNA modifications in Staphylococcus aureus using extensive oligonucleotide mass spectrometry, generating a high-confidence modification map for each individual tRNA species, including the non-proteogenic tRNAGly.
HostingRepositoryPRIDE
AnnounceDate2026-09-09
AnnouncementXMLSubmission_2026-09-09_04:23:22.253.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJose Refugio Jaramillo Ponce
SpeciesList scientific name: Staphylococcus aureus; NCBI TaxID: NEWT:1280;
ModificationListNo PTMs are included in the dataset
InstrumentSynapt G2-S HDMS
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-02 07:32:38ID requested
12026-09-09 04:23:23announced
Publication List
10.1093/nar/gkag757;
Jaramillo-Ponce JR, Wolff P, Marchand V, Motorin Y, Kohl M, Chane-Woon-Ming B, Kanazawa H, Ruiz-Paterson A, Paulus C, Chicher J, Lenon M, Kr, ä, mer M, Gribling-Burrer AS, Stathopoulos C, Smyth R, Helm M, Romby P, Marzi S, Comprehensive post-transcriptional modification profiles in individual Staphylococcus aureus tRNA species. Nucleic Acids Res, 54(14):(2026) [pubmed]
Keyword List
submitter keyword: LC-MSMS,tRNA modifications, Staphylococcus aureus
Contact List
Stefano Marzi
contact affiliationUPR 9002 CNRS-ARN Université De Strasbourg IBMC
contact emails.marzi@ibmc-cnrs.unistra.fr
lab head
Jose Refugio Jaramillo Ponce
contact affiliationUniversité de Strasbourg, CNRS, Architecture et Réactivité de l’ARN, 67000 Strasbourg, France
contact emailj.jaramillo@ibmc-cnrs.unistra.fr
dataset submitter
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Dataset FTP location
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