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PXD071449

PXD071449 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleUnveiling BCL-xL-specific PROTAC Efficiency and Dissociation Mechanisms Using Native Mass Spectrometry
DescriptionNative mass spectrometry enabled direct confirmation of PROTAC-mediated targeting of BCL-xL, while auxiliary activation methods dissected the disassembly of the ternary complexes, offering mechanistic insights.
HostingRepositoryjPOST
AnnounceDate2026-02-15
AnnouncementXMLSubmission_2026-02-15_18:31:49.361.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMohamed I. Gadallah
SpeciesList scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationListL-methionine residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-12-01 19:24:52ID requested
12026-02-15 18:31:49announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Native mass spectrometry, PROTACs, BCL-xL, Collision-induced dissociation, Ultraviolet photodissociation
Contact List
Jennifer S. Brodbelt
lab head
Mohamed I. Gadallah
contact affiliationUniversity of Texas at Austin
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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