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PXD071381

PXD071381 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleASNA1 Is Essential for Cardiac Development and Function by Regulating Tail-Anchored Protein Stability and Vesicular Transport in Cardiomyocytes
DescriptionProteomic analysis was performed on ventricular tissues isolated from embryonic day 14.5 (E14.5) cardiomyocyte-specific Asna1 conditional knockout mice and littermate controls. Heart lysates were digested with Trypsin/Lys-C and analyzed by LC-MS/MS using an EASY-nanoLC system coupled to an Orbitrap Fusion Lumos mass spectrometer. Label-free quantification (LFQ) was used to identify differentially expressed proteins associated with tail-anchored protein targeting, vesicular trafficking, and ER-Golgi transport pathways.
HostingRepositoryMassIVE
AnnounceDate2025-11-29
AnnouncementXMLSubmission_2025-11-29_08:14:17.613.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZeyu Chen
SpeciesList scientific name: Mus musculus; common name: house mouse; NCBI TaxID: 10090;
ModificationListunknown modification; unknown modification; unknown modification
Instrumentinstrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-28 20:47:39ID requested
12025-11-29 08:14:18announced
Publication List
no publication
Keyword List
submitter keyword: ASNA1, Cardiomyopathy, Tail-anchored proteins, Vesicular transport, Heart failure, DatasetType:Proteomics
Contact List
JU CHEN
contact affiliationUCSD
contact emailjuchen@ucsd.edu
lab head
Zeyu Chen
contact affiliationUCSD
contact emailzec018@ucsd.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive-ftp.ucsd.edu/v11/MSV000100049/