PXD071209

PXD071209 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Characterization of SPSB1-regulated proteins following CRISPR APA engineering
Description	Proteomics analysis was performed in 22Rv1, LNCaP-abl and BPH1 cells after transfection of 3'UTRCES-SPSB1 systems
HostingRepository	PRIDE
AnnounceDate	2026-06-29
AnnouncementXML	Submission_2026-06-28_16:42:10.822.xml
DigitalObjectIdentifier	https://doi.org/10.6019/PXD071209
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	FURONG HUANG
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-25 12:35:38	ID requested
⏵ 1	2026-06-28 16:42:12	announced

Publication List

10.6019/PXD071209;
Huang F, Yuan F, Li K, Cui Y, Li L, Ye W, Cui Z, Yan J, Chen Q, Nicchitta C, Zhang Y, Hankey W, Everitt J, Huang KL, Wang ME, Chen M, Huang J, Wang H, Wagner EJ, Lu X, Dong Y, Li W, Wang Q, Programmable mRNA 3'UTR engineering restores MHC-I and overcomes immune evasion in prostate cancer. Nat Biomed Eng, ():(2026) [pubmed]
10.1038/s41551-026-01720-9;

10.6019/PXD071209;

Huang F, Yuan F, Li K, Cui Y, Li L, Ye W, Cui Z, Yan J, Chen Q, Nicchitta C, Zhang Y, Hankey W, Everitt J, Huang KL, Wang ME, Chen M, Huang J, Wang H, Wagner EJ, Lu X, Dong Y, Li W, Wang Q, Programmable mRNA 3'UTR engineering restores MHC-I and overcomes immune evasion in prostate cancer. Nat Biomed Eng, ():(2026) [pubmed]

10.1038/s41551-026-01720-9;

Keyword List

submitter keyword: prostate cancer, CRISPR, alternative polyadenylation

submitter keyword: prostate cancer, CRISPR, alternative polyadenylation

Contact List

Qianben Wang
contact affiliation	Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College (PUMC)
contact email	qianben@ibms.pumc.edu.cn
lab head
FURONG HUANG
contact affiliation	Department of Pathology and Duke Cancer Institute, Duke University School of Medicine
contact email	furong.huang@duke.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD071209
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/06/PXD071209

PRIDE project URI

Repository Record List

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