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PXD071206

PXD071206 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleInput files: A modular, immunopeptidogenomic (iPepGen) analysis pipeline for discovery, verification, and prioritization of cancer peptide neoantigen candidates
DescriptionCharacterizing tumor-specific neoantigen peptides, which are derived from genomic or transcriptomic aberrations and presented to the immune system, is essential for studies in immuno-oncology. To facilitate this process, the modular iPepGen immunopeptidogenomics pipeline offers several key functions: (1) Neoantigen prediction and generation of a protein database from genomic or transcriptomic sequencing data; (2) Peptide identification; (3) Verification using immunopeptidomic mass spectral data; (4) Neoantigen classification and visualization; and (5) Candidate prioritization for further research. The pipeline is easily accessible through a publicly available, scalable cloud-based gateway and includes online interactive training materials. This streamlines adoption by cancer researchers, particularly those who may lack advanced computational expertise and resources for immunopeptidogenomic analysis.
HostingRepositoryMassIVE
AnnounceDate2026-02-02
AnnouncementXMLSubmission_2026-02-02_07:51:21.578.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSubina P Mehta
SpeciesList scientific name: HUMAN;
ModificationListNo PTMs are included in the dataset
Instrumentinstrument model
Dataset History
RevisionDatetimeStatusChangeLog Entry
02025-11-25 12:03:56ID requested
12026-02-02 07:51:22announced
Publication List
no publication
Keyword List
submitter keyword: Neoantigen, immunopeptidomics, immuno-oncology, mass spectrometry, next generation sequencing, multi-omics, Galaxy, bioinformatics, workflow, DatasetType:Proteomics
Contact List
Timothy J.Griffin
contact affiliationUniversity of Minnesota
contact emailtgriffin@umn.edu
lab head
Subina P Mehta
contact affiliationUniversity of Minnesota
contact emailsmehta@umn.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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