PXD071194 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative DIA/SWATH proteomic profiling of SAGA complex mutants in Cryptococcus neoformans |
| Description | This project investigates the proteomic consequences of deleting key subunits of the SAGA transcriptional coactivator complex (Hfi1, Spt7 and Spt20) in Cryptococcus neoformans. Quantitative SWATH/DIA LC-MS/MS was performed on wild-type and mutant strains grown at 30°C and 37°C to identify pathway-level alterations associated with impaired SAGA function. The dataset provides peptide- and protein-level quantification to support differential abundance analysis and functional interpretation of SAGA-dependent regulatory processes. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-01-03 |
| AnnouncementXML | Submission_2026-01-02_17:15:24.954.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chendi Yu |
| SpeciesList | scientific name: Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii); NCBI TaxID: NEWT:235443; |
| ModificationList | iodoacetamide derivatized residue |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-25 07:06:51 | ID requested | |
| ⏵ 1 | 2026-01-02 17:15:25 | announced | |
Publication List
Keyword List
| submitter keyword: Hfi1,Cryptococcus neoformans, SWATH, Spt20, Spt7, SAGA complex, DIA proteomics |
Contact List
| James Fraser |
|---|
| contact affiliation | The University of Queensland |
| contact email | j.fraser1@uq.edu.au |
| lab head | |
| Chendi Yu |
|---|
| contact affiliation | The University of Queensland |
| contact email | yuchendi4@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/01/PXD071194 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD071194
- Label: PRIDE project
- Name: Quantitative DIA/SWATH proteomic profiling of SAGA complex mutants in Cryptococcus neoformans
