PXD071028 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | LC-MS/MS of co-immunoprecipitation of 3xFLAG-UFM1 from ribosomal pellet in control and upon anisomycin treatment |
| Description | Clearance of arrested nascent polypeptides resulting from ribosomal stalling is essential for proteostasis. Stalled endoplasmic reticulum (ER)-bound ribosomes are marked by ubiquitin-fold modifier 1 (UFM1) on large ribosomal subunit protein RPL26, but the precise role of this process in ribosome-associated quality control (RQC) remains poorly understood. To identify proteins associated with UFMylated ribosomes, we isolated ribosomes from HCT116 cells expressing 3xFLAG-UFM1 upon stalling induction with anisomycin and in control conditions and preformed immunoprecipitation of 3xFLAG-UFM1. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-03-23 |
| AnnouncementXML | Submission_2026-03-23_07:20:47.131.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Richard Imre |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606; |
| ModificationList | monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2025-11-20 21:55:03 | ID requested | |
| ⏵ 1 | 2026-03-23 07:20:47 | announced | |
Publication List
Keyword List
| submitter keyword: UFM1, UFMylation, ribosome, anisomycin |
Contact List
| Guelsuen Elif Karagoez |
|---|
| contact affiliation | Max Perutz Laboratories Vienna, Vienna BioCenter, Vienna, Austria Medical University of Vienna, Vienna, Austria. |
| contact email | guelsuen.karagoez@meduniwien.ac.at |
| lab head | |
| Richard Imre |
|---|
| contact affiliation | IMBA Vienna |
| contact email | richard.imre@imba.oeaw.ac.at |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD071028
- Label: PRIDE project
- Name: LC-MS/MS of co-immunoprecipitation of 3xFLAG-UFM1 from ribosomal pellet in control and upon anisomycin treatment
