⮝ Full datasets listing
PXD070982
PXD070982 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Staphylococcus aureus Aggravates Atopic Dermatitis through Enhanced Bacterial Colonization |
| Description | Atopic dermatitis (AD), the most prevalent chronic inflammatory skin disease in children worldwide, is characterized by skin barrier dysfunction and microbial dysbiosis. Staphylococcus aureus colonizes lesional skin in up to 70% of AD patients, exacerbating inflammation through virulence factors (e.g., enterotoxin B, SplD protease) and biofilm formation, which disrupt the skin barrier and trigger Th2 immune responses. However, existing studies primarily focus on individual virulence factors, leaving the core regulatory mechanisms enabling persistent S. aureus colonization in AD poorly understood. |
| HostingRepository | iProX |
| AnnounceDate | 2025-11-20 |
| AnnouncementXML | Submission_2026-03-01_17:58:55.597.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Nadira Nurxat |
| SpeciesList | scientific name: Staphylococcus aureus; NCBI TaxID: 1280; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Orbitrap Astral |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-20 00:14:13 | ID requested | |
| ⏵ 1 | 2026-03-01 17:58:56 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Atopic Dermatitis, Staphylococcus aureus, adhesion |
Contact List
| Qian Liu | |
|---|---|
| contact affiliation | Shanghai Jiaotong University |
| contact email | qq2005011@163.com |
| lab head | |
| Nadira Nurxat | |
| contact affiliation | Shanghai Jiaotong University |
| contact email | nadira_next@163.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
