PXD070980

PXD070980 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Phosphorylation proteomic analysis of KCNN3-knockdown HCC cells to identify targeting proteins with phosphorylation changes
Description	In order to identify the targeted proteins that undergo phosphorylation changes caused by KCNN3, we conducted a phosphorylation proteomics analysis on Huh7 cells that had been knocked down for KCNN3.
HostingRepository	PRIDE
AnnounceDate	2026-08-24
AnnouncementXML	Submission_2026-08-23_16:15:02.182.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Wenbo Cheng
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: NEWT:9606;
ModificationList	phosphorylated residue
Instrument	timsTOF HT

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2025-11-20 00:10:17	ID requested
⏵ 1	2026-08-23 16:15:03	announced

Publication List

Zhan Z, Ge Y, Shi J, Liang H, Li Y, Jin J, Chen G, Zhai F, Kong L, Lin Y, Wang S, Chen L, Liu L, Chen K, Lou P, Ye M, Jin X, SPOP-mediated K27-linked non-degradative ubiquitination of KCNN3 suppressing HCC progression via the CTCF-SATB1 axis. Cell Death Dis, 17(1):(2026) [pubmed]
10.1038/s41419-026-08765-3;

Zhan Z, Ge Y, Shi J, Liang H, Li Y, Jin J, Chen G, Zhai F, Kong L, Lin Y, Wang S, Chen L, Liu L, Chen K, Lou P, Ye M, Jin X, SPOP-mediated K27-linked non-degradative ubiquitination of KCNN3 suppressing HCC progression via the CTCF-SATB1 axis. Cell Death Dis, 17(1):(2026) [pubmed]

10.1038/s41419-026-08765-3;

Keyword List

submitter keyword: HCC,KCNN3-knockdown, targeting proteins

submitter keyword: HCC,KCNN3-knockdown, targeting proteins

Contact List

Xiaofeng Jin
contact affiliation	Department of Biochemistry and Molecular Biology, Health Science Center, Ningbo University, Fenghua Road No.818, Ningbo, 315211, China.
contact email	jinxiaofeng@nbu.edu.cn
lab head
Wenbo Cheng
contact affiliation	Shanghai Omicsspace Bioteh CO., LTD
contact email	wbcheng@omicsspace.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD070980
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/08/PXD070980

PRIDE project URI

Repository Record List

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