⮝ Full datasets listing
PXD070808
PXD070808 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic analysis reveals immune response changes in silkworm pupae following treatment with Bacillus subtilis. |
| Description | Insects rely on innate immunity to defend against pathogens, with hemolymph playing a key role in immune responses. The silkworm (Bombyx mori) is a model organism for studying insect immunity, but research on immune-related proteins (especially antimicrobial peptides, AMPs) in silkworm pupae remains limited—despite pupae being rich in bioactive molecules with potential for antimicrobial development.To address this gap, we infected silkworm pupae with Bacillus subtilis (a Gram-positive bacterium) and used LC-MS/MS-based proteomics to analyze hemolymph proteins. The study aimed to identify immune-related proteins, clarify the pupal immune response dynamics, and provide insights for AMP discovery and application. |
| HostingRepository | iProX |
| AnnounceDate | 2025-11-15 |
| AnnouncementXML | Submission_2025-11-17_00:48:03.630.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Yuchen Li |
| SpeciesList | scientific name: Bombyx mori; NCBI TaxID: 7091; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2025-11-17 00:47:50 | ID requested | |
| ⏵ 1 | 2025-11-17 00:48:04 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Proteomics, Bombyx mori, Bacillus subtilis, immune-related proteins, antibacterial proteins |
Contact List
| Yan Zhang | |
|---|---|
| contact affiliation | Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, Biological Science Research Center, Southwest University, Chongqing, China |
| contact email | lyc041225@qq.com |
| lab head | |
| Yuchen Li | |
| contact affiliation | Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, Biological Science Research Center, Southwest University, Chongqing, China |
| contact email | lyc041225@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
